Phase 2 trial examines efficacy and response of bevacizumab/erlotinib for treatment of patients with rare subtypes of RCC. Despite an initial decrease in HRQOL after SABR, the procedure is more effective and less expensive than RFA & ... Professor Bex discusses the phase II NEOAVAX trial that evaluated avelumab/axitinib as neoadjuvant therapy in localized RCC. Samer Srour, MB, talks about the updated ALLO-316 and its use in targeting CD70 in patients with advanced ccRCC. Drs. Joyce and Jani look toward the future of liquid biopsy in RCC care and how new technology, like AI, will play a role. Drs. Joyce and Jani discuss practical clinical cases of using liquid biopsy to manage patients in different RCC settings. Drs. Joyce and Jani talk about the technique of liquid biopsy and its role as a diagnostic tool in RCC. The panel concludes with a candid discussion about the most urgent changes that could improve cancer care today. The panel explores the importance of introducing palliative care discussions earlier in the treatment journey. The panel explores the overlooked burden of financial toxicity and proactively raising the topic with patients. The panel explores how clinicians can build trust with patients from diverse backgrounds and ensure care is patient-centered. The panel explores how clinicians can introduce clinical trial options while maintaining trust in the face of uncertainty. The panel explores the emotional weight of a cancer diagnosis and the importance of empathetic communication. At 12 months, the OS rate for patients who received treatment with ipilimumab plus nivolumab was superior to SOC. The Two Onc Docs review the 5-year follow-up data on adjuvant pembro and a final analysis on ipi/nivo for metastatic disease. Dr. Machaalani highlights his study that evaluated the association between circulating KIM-1 and mRCC tumor biology. Dr. McGregor shares the opening of the STRIKE trial, which investigates adding tivo to pembro in the mRCC adjuvant setting. Dr. McGregor opens up about the expansion cohort of the phase 1 ARC-20 study, which looked at casdatifan plus cabozantinib. Dr. Chahoud talks about the results of the expansion cohort of the phase 1b STELLAR-002 study. Dr. Haas provides an update on a 5-year follow-up of KEYNOTE-564 and the survival benefits of adjuvant pembrolizumab for RCC.