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Non-Muscle Invasive Urothelial Carcinoma
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Reviewing the Role of PD-L1 in Patients With Urothelial Carcinoma
Katy Marshall
Muscle Invasive Urothelial Carcinoma
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July 25, 2024
Researchers evaluated the data of 50 specimens from patients who underwent TURBT and cystectomy for UC.
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Updated ENVISION Data: UGN-102 Shows 82.3% Duration of Response in LG-IR-NMIBC
Sandip Prasad, MD, MPhil
Non-Muscle Invasive Urothelial Carcinoma
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June 26, 2024
Dr. Prasad provides updates on the positive DOR data observed with UGN-102 for LG-IR-NMIBC in the ENVISION trial.
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ENVISION: Mitomycin Shows Promise as a Treatment for Patients With NMIBC
Katy Marshall
Non-Muscle Invasive Urothelial Carcinoma
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June 18, 2024
UroGen began the process of a rolling New Drug Application to the FDA for mitomycin as a treatment for patients with NMIBC.
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KEYNOTE-057: Outcomes for Patients With BCG-Unresponsive NMIBC Who Do Not Respond to Pembrolizumab
Roger Li, MD
Non-Muscle Invasive Urothelial Carcinoma
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June 6, 2024
Dr. Li describes his post hoc analysis and findings regarding patients with BCG–unresponsive, high-risk NMIBC in ...
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Final Results of CORE-001: Cretostimogene Plus Pembrolizumab for BCG-Unresponsive NMIBC With CIS
Roger Li, MD
Non-Muscle Invasive Urothelial Carcinoma
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June 6, 2024
Dr. Li details the final results of CORE-001, a phase-2, single arm study of cretostimogene combined with pembrolizumab.
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Urinary Cell-Free DNA Predicts Measurable Residual Disease in High-Risk Bladder Cancer With High Accuracy
Brandon Twyford
Non-Muscle Invasive Urothelial Carcinoma
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May 31, 2024
Urinary tumor DNA predicts residual bladder cancer pre-surgery, improving assessments and treatment, ASCO 2024 study finds
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Cretostimogene Grenadenorepvec With Pembrolizumab Offers Best-in-Class CR, DOR, for NMIBC
Emily Menendez
Non-Muscle Invasive Urothelial Carcinoma
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May 31, 2024
The CORE-001 trial began in 2020 to study the breakthrough therapy cretostimogene with pembrolizumab for high-risk NMIBC.
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MoonRISe-1: TAR-210 for Intermediate-Risk NMIBC
Roger Li, MD
Non-Muscle Invasive Urothelial Carcinoma
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May 28, 2024
Dr. Li rationalizes the design and potential impact of the MoonRISe-1 study for intermediate-risk NMIBC.
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MoonRISe-1: Evaluating the Promise of TAR-210 for Intermediate-Risk NMIBC
Roger Li, MD
Non-Muscle Invasive Urothelial Carcinoma
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May 21, 2024
Dr. Li provides commentary on the rationale, design, and impact of the MoonRISe-1 study for intermediate-risk NMIBC.
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KEYNOTE-057: Pembrolizumab Monotherapy Shows Promise for Patients With High-Risk NMIBC
Katy Marshall
Non-Muscle Invasive Urothelial Carcinoma
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May 14, 2024
The primary end point of the analysis of cohort B was 12-month disease-free survival.
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Next-Generation Immunotherapy for NMIBC: QUILT 2.005 and QUILT 3.032
Patrick Soon-Shiong, MD
Non-Muscle Invasive Urothelial Carcinoma
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May 10, 2024
Dr. Soon-Shiong provides an overview of the groundbreaking data related to nogapendekin alfa inbakicept for NMIBC.
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Urinary MRD Detection for Predicting Recurrence, Response to Nadofaragene Firadenovec in BCG-Unresponsive NMIBC
Vikram M. Narayan, MD
Non-Muscle Invasive Urothelial Carcinoma
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May 7, 2024
Continuing his discussion at the AUA 2024 Annual Meeting, Dr. Narayan highlights the latest news on nadofaragene firadenovec.
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Nadofaragene Firadenovec for BCG-Unresponsive NMIBC: 5-Year Follow-Up
Vikram M. Narayan, MD
Non-Muscle Invasive Urothelial Carcinoma
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May 7, 2024
Dr. Narayan breaks down the 5-year follow-up data on nadofaragene firadenovec for patients with BCG-unresponsive NMIBC.
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Developing, Validating AI Biomarkers to Predict Outcomes in BCG-Treated NMIBC
Yair Lotan, MD
Non-Muscle Invasive Urothelial Carcinoma
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May 7, 2024
Drs. Murray and Lotan review the development and validation of AI biomarkers to predict outcomes in BCG-treated NMIBC.
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Intravesical EMDA/MMC Safe, Feasible for BCG-Unresponsive NMIBC
Emily Menendez
Non-Muscle Invasive Urothelial Carcinoma
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May 3, 2024
Intravesical EMDA/MMC can serve as a safe and effective option for patients with high-risk NMIBC who fail BCG therapy.
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Intravesical Gemcitabine, Docetaxel for BCG-Naïve NMIBC
Zachary Bessette
Non-Muscle Invasive Urothelial Carcinoma
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May 3, 2024
A phase 2 clinical trial assessed combination intravesical gemcitabine and docetaxel for BCG-naïve NMIBC.
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Potential of uMRD to Predict Recurrence in BCG-Unresponsive NMIBC
Katy Marshall
Non-Muscle Invasive Urothelial Carcinoma
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May 3, 2024
uMRD profiling determines mutations connected with urothelial carcinoma through next-generation sequencing.
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Docetaxel, Gemcitabine, Cisplatin for Patients With BCG-Unresponsive NMIBC
Katy Marshall
Non-Muscle Invasive Urothelial Carcinoma
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May 3, 2024
Patients received weekly doses of docetaxel 80 mg, gemcitabine 1000 mg or 2000 mg, and biweekly cisplatin 100 mg.
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FDA Approves IL-15 Receptor Agonist for BCG-Unresponsive NMIBC
Zachary Bessette
Non-Muscle Invasive Urothelial Carcinoma
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April 23, 2024
The FDA approved Anktiva for patients with BCG-unresponsive NMIBC with CIS with or without papillary tumors.
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Molecular Testing and Treatment Sequencing for Advanced UC: Navigating FGFR-Targeted Therapy
Monika Joshi, MD, MRCP
Advanced Urothelial Carcinoma
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May 20, 2024
Dr. Joshi contextualizes the THOR study within the treatment landscape for FGFR2/3-altered advanced urothelial carcinoma.
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