Upper Tract Urothelial Carcinoma
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Drs. Murray and Broenimann highlight and evaluation of urinary genomic profiling for detection and molecular staging of UTUC.
Drs. Murray and Lotan highlight a recent multicenter study featuring longitudinal follow-up of UGN-101 for UTUC.
Dr. Lerner shares updates from the ENLIGHTED trial and analyses pertaining to NAC for UTUC from the ROBUUST registry.
For patients with clinical node-positive UTUC, NAC may lead to improved outcomes compared with adjuvant chemotherapy.
Padeliporfin VTP has previously shown positive safety and efficacy results for patients with low-grade UTUC.
Helen Gao highlights her comparative outcomes analysis of RNU and kidney-sparing surgery in the treatment of high-grade UTUC.
The only guideline-recommended endoluminal treatment option for patients with HG UTUC is bacillus Calmette-Guérin.
Patients who undergo RNU have comparative or better long-term outcomes than patients undergoing NSS for organ-localized UTUC.
The nomogram is used preoperatively to determine the probability of nodal tropism.
Previous trials have revealed that neoadjuvant chemotherapy is an effective treatment path for patients with high-grade UTUC.
Dr. Ferguson sheds light on a national analysis evaluating the role of lymph node dissection in patients with high-risk UTUC.
Dr. Djaladat discusses how the presence of specific biomarkers, such as CK|V oncosomes and D|CK|V cells, correlate with RFS.
Dr. Birtle describes the utility of carboplatin versus cisplatin in this regimen and discusses metastasis-free survival.
Dr. Birtle highlights the trial's findings regarding the long-term overall survival benefit of adjuvant chemotherapy.
The POUT trial investigated adjuvant chemo for improving disease-specific survival in patients with UTUC.
Liquid biopsy can benefit patients with UTUC by detecting rare events at higher incidences compared to tissue-based samples.
Patients in the POUT trial were randomized to either a platinum-based adjuvant chemotherapy arm or a surveillance arm.
Researchers investigated the ability of variant histology to predict oncological outcomes.
The system provides a seal of the upper urinary tract to prevent urine leakage and can prevent the spread of tumor cells.
Use of an sFI may increase accuracy in predicting complications and prognosis, as well as improve decision-making.
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