Roundtable
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The panel concludes with thoughts on the evolving role of lutetium-177 in metastatic castration-resistant prostate cancer.
The panel explores ARANOTE, ARASENS, and PEACE-1, emphasizing drug tolerability, toxicity trade-offs, and more.
The panel breaks down the growing role of MDT and the evolving use of radiation in oligometastatic disease.
The panel considers the ARANOTE trial of darolutamide, emphasizing its tolerability and broad eligibility criteria.
The panel examines the nuances of selecting triplet vs doublet therapy for patients with high-volume or high-risk disease.
The panel discusses how PSMA PET imaging is changing disease classification and decision-making.
The panel begins with how to explain the difference between hormone-sensitive and castration-resistant to patients.
The panel concludes with a discussion on the early use of PARP inhibitors in patients with DNA repair mutations like BRCA1/2.
The panel delves into how de novo metastases signal more aggressive prostate cancer biology.
The panel weighs the role of next-generation sequencing and emphasizes how SPOP, TP53, and RB1 guide treatment decisions.
The panel considers the evolving management of oligometastatic prostate cancer, highlighting the role of MDT.
The panel reviews treatment options for newly diagnosed mHSPC, comparing data from key doublet trials.
The panel explores scenarios where PSMA PET may not be needed, as well as limitations of conventional imaging in trials.
The panel discusses the evolving role of PSMA PET scans, imaging intervals, and distinguishing HSPC from CRPC.
The panel concludes with a discussion on the complexities of interpreting ctDNA positivity in earlier-stage bladder cancer.
The panel considers the adoption of bladder-sparing protocols and the potential of biomarkers to guide risk stratification.
The panel debates the management of high-grade T1 bladder cancer with lymphovascular invasion and variant histology.
The panel pivots to complex considerations in bladder cancer treatment, weighing the promise of IO in BCG-naïve patients.
The panel shares how patient lifestyle, bladder symptoms, and other factors influence intravesical therapy selection.
The panel explores the challenges of delivering bladder-sparing therapies like gem/doce and TAR-200 in real-world settings.
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