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Upper Tract Urothelial Carcinoma
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RNU Versus Kidney-Sparing Surgery for High-Grade UTUC
Helen Gao
Upper Tract Urothelial Carcinoma
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April 24, 2024
Helen Gao highlights her comparative outcomes analysis of RNU and kidney-sparing surgery in the treatment of high-grade UTUC.
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Evaluating Gemcitabine, Docetaxel Versus Bacillus Calmette-Guérin in Patients With UTUC
Katy Marshall
Upper Tract Urothelial Carcinoma
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April 19, 2024
The only guideline-recommended endoluminal treatment option for patients with HG UTUC is bacillus Calmette-Guérin.
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Long-term Outcomes of Nephron-Sparing Surgery Versus RNU for Organ-Localized UTUC
Zachary Bessette
Upper Tract Urothelial Carcinoma
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April 8, 2024
Patients who undergo RNU have comparative or better long-term outcomes than patients undergoing NSS for organ-localized UTUC.
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Novel Nomogram Predicts Lymph Node Invasion in UTUC
Emily Menendez
Upper Tract Urothelial Carcinoma
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April 8, 2024
The nomogram is used preoperatively to determine the probability of nodal tropism.
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Perioperative Chemotherapy for Patients With UTUC, Nephroureterectomy
Katy Marshall
Upper Tract Urothelial Carcinoma
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April 8, 2024
Previous trials have revealed that neoadjuvant chemotherapy is an effective treatment path for patients with high-grade UTUC.
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SESAUA 2024: Role of LND in Patients with High-Risk UTUC
James “Jed” Ferguson III, MD, PhD
Upper Tract Urothelial Carcinoma
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March 29, 2024
Dr. Ferguson sheds light on a national analysis evaluating the role of lymph node dissection in patients with high-risk UTUC.
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Blood-Based Liquid Biopsy for Patients With UTUC
Hooman Djaladat, MD
Upper Tract Urothelial Carcinoma
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March 28, 2024
Dr. Djaladat discusses how the presence of specific biomarkers, such as CK|V oncosomes and D|CK|V cells, correlate with RFS.
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Carboplatin Versus Cisplatin in UTUC
Alison Jane Birtle, MD, MBBS, MRCP, FRCR
Upper Tract Urothelial Carcinoma
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March 15, 2024
Dr. Birtle describes the utility of carboplatin versus cisplatin in this regimen and discusses metastasis-free survival.
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Potential OS Benefit of Adjuvant Chemotherapy for UTUC
Alison Jane Birtle, MD, MBBS, MRCP, FRCR
Upper Tract Urothelial Carcinoma
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March 21, 2024
Dr. Birtle highlights the trial's findings regarding the long-term overall survival benefit of adjuvant chemotherapy.
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POUT: Adjuvant Chemotherapy After Nephroureterectomy for Patients With UTUC
Alison Jane Birtle, MD, MBBS, MRCP, FRCR
Upper Tract Urothelial Carcinoma
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March 15, 2024
The POUT trial investigated adjuvant chemo for improving disease-specific survival in patients with UTUC.
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Blood-Based Liquid Biopsies Detect CTCs, Oncosomes in Patients With UTUC
Emily Menendez
Upper Tract Urothelial Carcinoma
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March 11, 2024
Liquid biopsy can benefit patients with UTUC by detecting rare events at higher incidences compared to tissue-based samples.
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Adjuvant Chemotherapy May Improve Overall Survival in UTUC
Katy Marshall
Upper Tract Urothelial Carcinoma
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March 1, 2024
Patients in the POUT trial were randomized to either a platinum-based adjuvant chemotherapy arm or a surveillance arm.
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Prognostic Capabilities of Variant Histology for Patients With UTUC
Katy Marshall
Upper Tract Urothelial Carcinoma
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March 11, 2024
Researchers investigated the ability of variant histology to predict oncological outcomes.
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Hem-o-lok System Prevents Spread of Tumor Cells in Radical Nephroureterectomy for UTUC
Emily Menendez
Upper Tract Urothelial Carcinoma
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December 20, 2023
The system provides a seal of the upper urinary tract to prevent urine leakage and can prevent the spread of tumor cells.
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Five-Item Frailty Index Can Increase Prognosis, Decision-Making in Patients With UTUC After RNU
Emily Menendez
Upper Tract Urothelial Carcinoma
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December 12, 2023
Use of an sFI may increase accuracy in predicting complications and prognosis, as well as improve decision-making.
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Defining the Biology of Upper Tract Urothelial Carcinoma and Therapy Implications
Christopher Wallis, MD, PhD, FRCSC
Upper Tract Urothelial Carcinoma
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March 11, 2024
Drs. Faltas and Wallis delve into the genomics of UTUC, including the evolution of disease and FGFR inhibition potential.
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Nephron-Sparing and Chemoablation in Upper Tract Urothelial Carcinoma
Christopher Wallis, MD, PhD, FRCSC
Upper Tract Urothelial Carcinoma
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December 18, 2023
Drs. Murray and Wallis discuss optimal patient selection, size criteria, and surgical ablation and chemoablation together.
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Nomogram Finds Suitable Candidates for Endoscopic Management of LG-NMI UTUC
Emily Menendez
Upper Tract Urothelial Carcinoma
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December 12, 2023
The nomogram outperformed 2 conventional models in predictive accuracy and showed higher benefit in decision curve analysis.
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Novel Use of ctDNA to Identify Muscle-Invasive, Non–Organ-Confined UTUC
Roger Li, MD
Upper Tract Urothelial Carcinoma
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March 11, 2024
Dr. Li details what his study results suggested about ctDNA’s prognostic implications for survival in patients with UTUC.
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Ureteroscopic Surgery for Patients With UTUC
Katy Marshall
Upper Tract Urothelial Carcinoma
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November 14, 2023
The study compared ureteroscopic surgery with radical nephroureterectomy.
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